Immunological diagnosis of CMV infection in HIV-infected patients
نویسندگان
چکیده
Background The Quantiferon-CMV assay is a test for Cell Mediated Immune (CMI) responses to peptide antigens that simulate CMV proteins. Individuals infected with CMV usually have CD8+ lymphocytes in their blood that recognize these antigens. This recognition process involves the generation and secretion of the cytokine and interferon (IFN). The detection and subsequent quantification of IFN forms the basis of this test.
منابع مشابه
Cytomegalovirus Active Infection in Persons Infected with Human Immunodeficiency Virus
Background and Objective: Cytomegalovirus (CMV), one of the most common opportunistic pathogens in patients infected with human immunodeficiency virus (HIV), can cause the diseases such as encephalitis, pneumonia, and chorioretinitis. This study aimed at molecular studying of CMV infection in individuals infected with the human immunodeficiency virus. Material and Methods: In this study, 50 ven...
متن کاملSero-prevelance of Cytomegalovirus and Toxoplasma Infections among Newly Diagnosed HIV Patients in Iran; Assessing the Correlation with CD4+ Cell Counts
Background and Objective: Opportunistic infections are the leading cause of death among patients subjected to the human immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS). The aim of this study was to compare the seroprevalence of Cytomegalovirus (CMV) and toxoplasmosis infection in newly diagnosed HIV infected patients with healthy controls and it’s correlat...
متن کاملبررسی وضعیت سرواپیدمیولوژی سیتومگالو ویروس در بیماران HIV مثبت استان یزد از سال 1381 لغایت 1394
Introduction: Currently, cytomegalovirus (CMV) is recognized as an important pathogens in all age groups throughout the world. Living as group and lack of health facilitate the rapid spread of infection. CMV-reactive syndromes are commonly associated with the development of T-dependent immune deficiencies, such as those infected with HIV. The CMV alone can also reduce T lymphocyte responses. Th...
متن کاملThe Prevalence and Risk Factors of Hepatitis Delta Virus in HIV/HBV Co-Infected Patients in Shiraz, Iran, 2012
Evidence has shown that liver disease caused by hepatitis viruses can be more aggressive and severe in HIV infected subjects. Therefore, the present cross-sectional study aimed to evaluate the seroprevalence of HDV infection among HIV/HBV co-infected clients in Shiraz, southwest Iran. In this study, 178 patients co-infected with HBV and HIV individuals were enrolled. The diagnosis of HIV infect...
متن کاملCytomegalovirus infection in HIV-infected versus non-infected infants and HIV disease progression in Cytomegalovirus infected versus non infected infants early treated with cART in the ANRS 12140—Pediacam study in Cameroon
BACKGROUND The outcome of CMV/HIV co-infection in infants treated early with combined antiretroviral therapy (cART) in resource-limited settings has not been described. We aimed to estimate the prevalence and identify factors associated with early CMV infection in HIV-infected and non-infected infants included in a study in Cameroon, and to compare HIV disease progression and survival after 1 y...
متن کامل